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  3. What is Intracytoplasmic sperm injection? (ICSI)

What is Intracytoplasmic sperm injection? (ICSI)

How successful is ICSI ? Get complete information about ICSI with detailed procedure, technique, risk & precaution. Now no more confusion between IVF & ICSI .

  • Ivf (In Vitro Fertilization)

By Pankaj Kamble

2nd May '20

Is IVF and ICSI the same technique ???

Usually, most of us have questions related to IVF specially the ones who are not able to conceive naturally. Moreover,many people are confused between these two techniques(ICSI and IVF). However, both the treatments have good success rates. But, there is a major difference in technique when it comes to fertilization of the egg outside the body . In ICSI the individual sperm is directly injected into the egg to help it fertilize.

 

So, exactly what is ICSI? And how this treatment is different from the conventional IVF ?

 

Dr. Alex Polyakov, Clinical Director of Melbourne IVF, says that -

ICSI is a specialized form of in vitro fertilization (IVF) that is used primarily for the treatment of severe cases of male-factor infertility. ICSI involves the injection of a single sperm directly into a mature egg.

In conventional IVF, the eggs and sperm are mixed together in a petri dish and the sperm fertilizes the egg naturally. However, in ICSI, a single sperm is selected and injected directly into the egg. This method bypasses the natural fertilization process and is used in cases where the sperm may not be able to penetrate the egg on its own.

There are many couples from all around the world who are facing issues while conceiving and one of the reasons for infertility is sperm-related. The treatment which is most common and successful for male infertility is ICSI (intracytoplasmic sperm injection).

IVF and ICSI both are types of assisted reproductive treatment (ART).

 

The main reason for ICSI to come into the picture is when IVF treatment fails in the case of severe male infertility. Also, the other reasons that are nowadays seen are immunological infertility, ejaculatory dysfunction, and treatments required for cancer patients.

ICSI technique is generally recommended by doctors to :

  • Males having a low sperm count.
  • Woman who have under gone IVF treatment before and none or only a few eggs fertilized.
  • The ones whose sperm quality is poor i.e shape of sperm is abnormal ( poor morphology) and also the movement of the sperm is not normal (poor motility).
  • Further, for people who have frozen their sperm before undergoing chemotherapy or radiotherapy.
  • Further, for people who have frozen their sperm before undergoing chemotherapy or radiotherapy.
  • Also, for male partner suffering from azoospermia. AZOOSPERMIA is a condition where there is no sperm in the male's ejaculation. So people suffering from this are also recommended to go for ICSI.
Advantages of ICSI - Helps in male infertility, Fertilization is improved, Incase IVF treatment have failed

Now surely you must have got an idea about ICSI technique.

 

But you surely must be wondering what exactly is the procedure for ICSI? Or what are the steps for ICSI technique ?

 

ICSI is an advance fertility method which falls under ASSISTED REPRODUCTIVE TECHNIQUE in which a singular sperm cell is introduced directly into the egg.

 

Given below are some of the risk related with ICSI

The success rate of ICSI is high i.e around 50 to 80 percent but it is not necessary that all the fertilized eggs will get developed into healthy embryos. Also, this technique helps in fertilizing egg even if the sperm is not healthy enough which could result in defective embryos.

 

Further, the risk associated with ICSI is the same as that of children conceived naturally. But the child conceived by ICSI would have very low birth defects, less than 1%. According to researchers, the birth defects can be because of sex chromosome abnormalities, urinary system or genitals defects and lower quality sperm. But there are rare chances that this will happen.

 

However, the main risk associated with ICSI is actually a risk of IVF itself because of an increased chance of multiple births. This risk can be minimized by cautiously and attentively controlling the number of embryos that are to be transferred in the female's uterus. Multiple births i.e twins, triplets or more than that results in a high rate of risk and complications to both mother and babies.
 

Precautions to be taken after an ICSI treatment are :

  • Smoking should be avoided along with the consumption of alcohol.
  • Before taking any medication always consult your doctor.
  • Exercises like jogging, aerobics and weight lifting are strictly prohibited.

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Question and Answers

Dear Sir, I trust this message finds you well. I am writing to seek further advice or guidance regarding a matter that has been concerning my wife and me deeply. Since our marriage in April 2024, we have encountered challenges in conceiving a child. Following consultations with a gynecologist, my wife underwent various tests, all of which returned normal results. However, based on the recommendation of the gynecologist, I underwent a semen analysis test. The results indicated a total sperm count of 45 million, falling below the normal range of 60 to 150 million. Additionally, the motility percentage was recorded at 0%, significantly lower than the normal range of greater than 25%. In search of a solution, I sought advice from two different medical professionals, both of whom prescribed distinct medications and treatments. The first doctor recommended a daily intake of one tablet each of YTIG and CQ10 (100gm). Conversely, the second doctor advised me to consume 10 drops of two different oils, Agnus castus and Damiana, with water twice a day. For your reference, I am a 34-year-old male, measuring 5 feet 11 inches in height and weighing 94 kilograms. Despite diligently adhering to the prescribed treatments, my wife has not yet conceived. Therefore, I would greatly appreciate any further advice or guidance you may offer on this matter. Thank you sincerely for your attention and assistance. Warm regards, Habib Bughio

Male | 34

According to the given information, it's advised for you to instance get the help of a fertility specialist. Since that time, they will be capable of performing a full examination and help you to develop for your particular case.

Answered on 16th Apr '24

Dr. Mohit Saraogi

Dr. Mohit Saraogi

Why am I unable to get pregnant

Female | 22

There may be several reasons to explain why you can't conceive. It is crucial that you go and get examined by a fertility doctor or a gynecologist and get your infertility cause to be diagnosed. Whether you opt for IUI or IVF, they will offer you counseling and explain the available methods to enhance your chances of conceiving.

Answered on 16th Apr '24

Dr. Mohit Saraogi

Dr. Mohit Saraogi

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